...On a superficial level, however, we do know how acne occurs, so let's get that out of the way first. In very basic terms, acne develops when the pores of the skin are clogged. Beneath every pore of your skin lies a canal-like structure called a follicle, within which lie a hair and an oil gland. The oil gland is actually a sebaceous gland, which secretes an oily substance called sebum, which moisturizes the skin and helps remove dead skin cells. However, there are times when the sebaceous gland secretes excess oil, which is when your troubles begin....»
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«...Inflammation Is the Result of a Multi-faceted ProcessHormonal changes are at the root of acne pathogenesis.The primary target of acne is the pilosebaceous unit of the follicle.Hormones stimulate increased production of lipids in the follicle.Inflammation probably arises from the presence of prostaglandins and cytokines that are attracted to the lipids within the follicle.Some individuals may be genetically prone to overactive inflammatory pathways, which increases their chances of having severe inflammatory acne....»
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